Trains between Düsseldorf and Hamburg go daily, several times a day. The whole route can be traversed without a transfer or just one, in Hanover. The travel time will be 3 hours 40 minutes or 4 hours

The ticket for the second class seat on the direct train InterCity (IC) will cost the passenger at 44-78 EUR depending on the booking conditions. That is, from when the ticket is bought (if the same day, the price is maximal), whether it will be possible to hand over it, change the place, for which reservation, by the way, it will be necessary to pay 4 EUR. First-class tickets without a transfer cost from 69-126 EUR