Bus lines from Antwerp to Cologne (Germany) are currently not very developed. This is explained by the fact that in Germany for several years the monopoly was held by the Deutsche Bahn railway carrier. But on the train the journey will be very comfortable and fast enough.

If the trip between the above cities is basically done by bus, it can be done on the tourist bus (often they go not directly to Cologne, but through Amsterdam or Dusseldorf). Another option is to rent a car. Germany is not in vain famous for its magnificent roads!